More and more clinics are now discovering our products, VitriBlast and ThermoBlast for vitrification of blastocysts.

One of them is IVF clinic Falun, a private clinic in Sweden. They presented a study at the Nordic meeting earlier this year where they had compared slow freezing and vitrification using DMSO and vitrification using PrOH.

Background: The clinic has successfully used slow freezing for cryopreservation of blastocyst and before implementing a new method the methods were evaluated.

Study question: Does slow freezing of human blastocysts give comparable results to those of vitrification? Does vitrification with DMSO yield better results than with PrOH?

Main outcome measures: Cryosurvival, implantation and birth rates.

Design and setting: Prospective randomized pilot study at a private IVF clinic.

Methods: 300 IVF cycles were randomized into three groups, slow freezing, vitrification with DMSO and vitrification with PrOH.

Blastocysts were frozen or vitrified according to the clinic’s protocol using a closed system. The frozen cycles were conducted with single embryo transfers.

Results: The results showed no significant difference between groups with regards to implantation and live birth rates. Blastocysts vitrified with DMSO showed significantly higher survival rates than blastocyst vitrified with PrOH.