Summary

SpermCatch™ is a natural alternative to polyvinyl plastic for slowing sperm for ICSI.

Until now, the only products available for slowing sperm motility contained polyvinylpyrrolidone. Clinicians are concerned that injecting this artificial product into the oocyte along with the sperm may cause damage to acrosomal, mitochondrial and plasma membranes, as well as to the chromosomal DNA.

Now clinicians have an alternative method for modulating sperm motility.

Due to the stable formulation the shelf-life is as long as 1 year

SpermCatch™ contains only substances normally found in the mammalian reproductive tract. Exposure of sperm to SpermCatch™, not only slows sperm, but also mimics the naturally occurring sequence of events during in vivo fertilization.

Components

- Ions of calcium, carbonate, chloride, magnesium,phosphate, potassium, sodium & sulphate

- hSA Human serum albumin
- Purified water
- Glucose
- Lactate
- Pyruvate
- EDTA
- HEPES
- Hyaluronic Acid

Performance Characteristics

pH: 7.0 - 8.5
Osmolality (mOsm/kg H2O): 300-320
Endotoxin levels: <1.0 EU/mL
Sperm survival 18 hours after density gradient separation: > 50%

Contents are tested by human sperm survival only

Bottles and stoppers are 2-cell M.E.A. tested

Protein Supplement

SpermCatch™ contains the component human serum albumin. (hSA). The human serum albumin is manufactured from human blood donated in the United States. The blood donors who supply the human plasma are tested for various viruses before being allowed to donate blood for this purpose. Each plasma donation is individually tested for ALT, HBs antigen, HIV-1/2 antibody and HCV antibody by ELISA. Only those plasma donations found non-reactive for those antibodies have been used for the manufacture of the hSA component. The plasma pool is tested again before manufacture of the hSA product. The hSA product is heated at 60ºC for 10 hours as a final precaution.

Storage and Stability

Store unopened bottles at 2 to 30ºC and avoid temperatures above or below these values. Under these conditions SpermCatch™ has a shelf-life of 12 months. The expiry date is shown on both bottles and cartons.

Open and close bottles under aseptic conditions. After opening, store at 2 to 8ºC when not in use. Shelf-life on the product label applies when the product is stored according to manufacturer’s recommendations.

No antibiotics, unstable additives or preservatives have been added by the manufacturer to SpermCatch™.

Precautions and Warnings

- Use aseptic procedures at all times

- SpermCatch™ does not represent any fire or combustion hazard. A material safety data sheet is available from the distributor or manufacturer (see nidacon.com)

- Do not use any solution which shows evidence of bacterial contamination

- Do not use contents if tamper-evident seal is broken

- Federal Law (USA) restricts this device to sale by or on the order of a physician

- Please check for regulatory compliance governing the use of ART products in your country

Ordering Information

Article No. / Name / Volume
SC-100 / SpermCatch™ / 6 × 100 µl

Human Products

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